Publications of Jan Zarzycki

Schulz, L.; Zarzycki, J.; Steinchen, W.; Hochberg, G. K. A.; Erb, T. J.: Layered entrenchment maintains essentiality in the evolution of Form I Rubisco complexes. The EMBO Journal 44, pp. 269 - 280 (2025)

Lago-Maciel, A.; Soares, J. C.; Zarzycki, J.; Buchanan, C. J.; Reif-Trauttmansdorff, T.; Schmidt, F. V.; Lometto, S.; Paczia, N.; Schuller, J. M.; Hansen, D. F. et al.; Heller, G. T.; Prinz, S.; Hochberg, G. K. A.; Pierik, A. J.; Rebelein, J. G.: Methylthio-alkane reductases use nitrogenase metalloclusters for carbon-sulfur bond cleavage. bioRxiv: the preprint server for biology, 2024.10.19.619033 (2024)

He, H.; Gómez-Coronado, P. A.; Zarzycki, J.; Barthel, S.; Kahnt, J.; Claus, P.; Klein, M.; Klose, M.; de Crécy-Lagard, V.; Schindler, D. et al.; Paczia, N.; Glatter, T.; Erb, T. J.: Adaptive laboratory evolution recruits the promiscuity of succinate semialdehyde dehydrogenase to repair different metabolic deficiencies. Nature Communications 15 (1), 8898 (2024)

Schmidt, F. V.; Schulz, L.; Zarzycki, J.; Prinz, S.; Oehlmann, N. N.; Erb, T. J.; Rebelein, J. G.: Structural insights into the iron nitrogenase complex. Nature Structural & Molecular Biology 31 (1), pp. 150 - 158 (2024)

Nattermann, M.; Wenk, S.; Pfister, P.; He, H.; Lee, S.H.; Szymanski, W.; Guntermann, N.; Zhu, F.; Nickel, L.; Wallner, C. et al.; Zarzycki, J.; Paczia, N.; Gaißert, N.; Franciò, G.; Leitner, W.; Gonzalez, R.; Erb, T. J.: Engineering a new-to-nature cascade for phosphate-dependent formate to formaldehyde conversion in vitro and in vivo. Nature Communications 14 (1), 2682 (2023)

Marchal, D. G.; Schulz, L.; Schuster, I.; Ivanovska, J.; Paczia, N.; Prinz, S.; Zarzycki, J.; Erb, T. J.: Machine learning-supported enzyme engineering toward improved CO₂-fixation of Glycolyl-CoA carboxylase. ACS Synthetic Biology 12 (12), pp. 3521 - 3530 (2023)

Kremer, K.; Meier, D.; Theis, L.; Miller, S.; Rost-Nasshan, A.; Naing, Y. T.; Zarzycki, J.; Paczia, N.; Serrania, J.; Blumenkamp, P. et al.; Goesmann, A.; Becker, A.; Thanbichler, M.; Hochberg, G. K. A.; Carter, M. S.; Erb, T. J.: Functional degeneracy in Paracoccus denitrificans Pd1222 is coordinated via RamB, which links expression of the Glyoxylate cycle to activity of the Ethylmalonyl-CoA pathway. Applied and Environmental Microbiology 89 (7), e0023823 (2023)

McLean, R.; Schwander, T.; Diehl, C.; Cortina, N. S.; Paczia, N.; Zarzycki, J.; Erb, T. J.: Exploring alternative pathways for the in vitro establishment of the HOPAC cycle for synthetic CO₂ fixation. Science Advances 9 (24), eadh4299 (2023)

Pfister, P.; Zarzycki, J.; Erb, T. J.: Structural basis for a cork-up mechanism of the intra-molecular Mesaconyl-CoA transferase. Biochemistry 62 (1), pp. 75 - 84 (2023)

Schulz, L.; Guo, Z.; Zarzycki, J.; Steinchen, W.; Schuller, J. M.; Heimerl, T.; Prinz, S.; Mueller-Cajar, O.; Erb, T. J.; Hochberg, G. K. A.: Evolution of increased complexity and specificity at the dawn of form I Rubiscos. Science 378 (6616), pp. 155 - 160 (2022)

Nattermann, M.; Burgener, S.; Pfister, P.; Chou, A.; Schulz, L.; Lee, S. H.; Paczia, N.; Zarzycki, J.; Gonzalez, R.; Erb, T. J.: Engineering a highly efficient carboligase for synthetic one-carbon metabolism. ACS Catalysis 11 (9), pp. 5396 - 5404 (2021)

Scheffen, M.; Marchal, D. G.; Beneyton, T.; Schuller, S.K.; Klose, M.; Diehl, C.; Lehmann, J.; Pfister, P.; Carillo, M.; He, H. et al.; Aslan, S.; Cortina, N. S.; Claus, P.; Bollschweiler, D.; Baret, J.-C.; Schuller, J.M.; Zarzycki, J.; Bar-Even, A.; Erb, T. J.: A new-to-nature carboxylation module to improve natural and synthetic CO₂ fixation. Nature Catalysis 4, pp. 105 - 115 (2021)

Stoffel, G. M. M.; Saez, D. A.; DeMirci, H.; Voegeli, B.; Rao, Y.; Zarzycki, J.; Yoshikuni, Y.; Wakatsuki, S.; Vohringer-Martinez, E.; Erb, T. J.: Four amino acids define the CO₂ binding pocket of enoyl-CoA carboxylases/reductases. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116 (28), pp. 13964 - 13969 (2019)

Erb, T. J.; Zarzycki, J.: A short history of RubisCO: the rise and fall (?) of Nature's predominant CO₂ fixing enzyme. CURRENT OPINION IN BIOTECHNOLOGY 49, pp. 100 - 107 (2018)

Erb, T.J.; Zarzycki, J.: Biochemical and synthetic biology approaches to improve photosynthetic CO₂-fixation. Current Opinion in Chemical Biology 34, pp. 72 - 79 (2016)

Erb, T. J.; Zarzycki, J.: Biochemical and synthetic biology approaches to improve photosynthetic CO₂-fixation. Curr Opin Chem Biol 34, pp. 72 - 79 (2016)

Erb, T. J.; Zarzycki, J.; Scheffen, M.: 5 Synthetic enzymes and pathways for improved carbon capture and conversion. In: Photosynthesis: Biotechnological Applications with Microalgae, pp. 129 - 146 (Ed. Matthias, R.). De Gruyter (2021)

Schada von Borzyskowski, L.; Erb, T. J.; Zarzycki, J.: Method of producing autotrophic organisms with altered photorespiration and improved CO₂ fixation. US20210163956A1 (2021)

Küffner, A. M.; Pommerenke, B.; Kley, L.; Ng, J. Z. Y.; Prinz, S.; Tinzl-Zechner, M.; Claus, P.; Paczia, N.; Zarzycki, J.; Hochberg, G. K. A. et al.; Erb, T. J.: Bottom-up reconstruction of minimal pyrenoids provides insights into the evolution and mechanisms of carbon concentration by EPYC1 proteins. bioRxiv: the preprint server for biology, 2024.06.28.601168 (2024)

Schulz, L.; Zarzycki, J.; Steinchen, W.; Hochberg, G. K. A.; Erb, T. J.: Layered entrenchment maintains essentiality in protein-protein interactions. bioRxiv: the preprint server for biology, 2024.01.18.576253 (2024)